Research Network for Metals in Medicine

 

 

Associate Professor Jack Ng

Position: Metals and Metalloids research group leader

Affiliation: National Research Centre for Environmental Toxicology

Postal Address:
National Research Centre for Environmental Toxicology (EnTox)
39 Kessels Road
Coopers Plains
Brisbane Queensland 4108
AUSTRALIA

Phone: +61 (07) 3274 9020
Email: j.ng@uq.edu.au
Webpage: http://www.uq.edu.au/nrcet/DrJackNg.html


Research Profile

Jack Ng is an experienced environmental toxicologist who has a wide range of analytical, chemical and biological skills. Jack has been responsible for the establishment of the laboratory infrastructure in EnTox with the Faculty of Health Sciences and is currently the Program Leader of Metals and Metalloids including arsenic research at the Centre. Jack has a significant contribution to the scientific knowledge of arsenic toxicity by developing the first competent animal model for arsenic carcinogenicity. Jack is an internationally recognised arsenic expert. He recently focuses on toxicity of mixtures including mixed metals. He has extensive research experience in the fields of environmental toxicology and chemistry, heavy metals and natural toxins and extensive interest in risk assessment of contaminants. He has been appointed as Study Director for toxicology testing of chemicals in accordance with OECD guidelines. He is the EnTox coordinator responsible for getting NATA certification for GLP for this testing facility. He has been a member of the Animal Ethics Committee since 1993. Jack is an experienced consultant and trainer of specialists/professionals in multi-million dollars international (AusAID) and national projects. Jack has written a number of book chapters and about 200 scientific publications and reports. He was invited by WHO to act as a coordinator and to contribute three chapters in the IPCS EHC (environmental health criteria) document on arsenic. His arsenic publications have been cited in significant documents prepared by international agencies: NRC (1999), ATSDR (2000), USEPA (2001) and WHO/IPCS EHC224 (2001). He is currently the Toxicology Program Manager for an AusAID funded “Arsenic Mitigation Program in Bangladesh” ($1,470,000 over 3 yrs). He is a CI in four ARC funded research projects involving arsenic and mixed metals. His current projects involve collaboration nationally and internationally including UQ, Monash University, ANU, Central Queensland University, USA, Bangladesh and China. He had also conducted projects and specialists training in Indonesia. Jack has been invited to numerous international conferences. He was a member of WHO/IPCS Task Group for the EHC document; co-chair, WHO International Workshop on the toxicology of arsenic, 1999, Australia; chair, International Conference on Toxicology of Metals and Metalloids, 2001, Australia; organising committee, International Conference on Environmental and Public Health Management, 2002, Hong Kong; organizer and chair, Arsenic Symposium of 15th Conference of International Society for Environmental Epidemiologists, 2003, Australia; Task Group Member, WHO Global Information Network on Chemical Safety, Japan; author and Working Group Member of IARC Monograph 84 on “Some drinking water disinfectants and contaminants including arsenic (2003)”, France; session chair, International Arsenic Conference, USA (2000 & 2002); Guest Editor, special issue on arsenic in Toxicology Letters (2002); and Guest Editor, Metals and Metalloids in the same journal (2003). Jack is a referee for numerous international journals and reviewer for several granting bodies nationally and internationally including NHMRC grants.

Selected Publications

  1. Jack C. Ng, Michael R. Moore, Xianglin Shi (Guest Editors) (2003). Special issue on “Environmental Toxicology of Metals and Metalloids”, Toxicology Letters, Vol 137. (11 papers).
  2. Ng J.C. (one of Contributing Authors) (2003). WHO IARC Monograph 84: Some drinking water disinfectants and contaminants including arsenic – in press.
  3. Jack C. Ng (2002). Health risk assessment. Chapter 3. In: The Restoration and Management of derelict lands: Modern Approaches. M.H. Wong and A.D. Bradshaw (eds.), World Scientific Publishing Co, Singapore. Pp 19-30. Tran H.P., Prakash A.S., Barnard R.
  4. Ng J.C. (2002). Arsenic inhibits the repair of DNA damage induced by benzo(a)pyrene. Toxicology Letters, 133: 59-67.
  5. Zheng Y.J., Wu J., Ng J.C., Wang G.Q., Lian W. (2002). Absorption and excretion of fluoride and arsenic in humans. Tox. Lett., 133: 77-82.
  6. Ng J.C., Qi L. Moore M.R., 2002, Porphyrin profile in blood and urine as a biomarker for exposure to various arsenic species. J. Cell Mol. Biol. 48(1): 111-23.
  7. Ng J.C., 2001, WHO IPCS EHC on Arsenic and Arsenic Compounds, Editor and author, 521 pages.
  8. Oelrichs PB, MacLeod JK, Seawright AA, Moore MR, Ng J.C., Dutra F, Riet-Corréa F, Mendez MC and Thamsborg SM, 1999, Unique toxic peptides isolated from sawfly larvae in three continents. Toxicon, 37, 537-544. Toxicon, 37, 537-544.
  9. Ng J.C., Seawright AA, Qi L, Garnett CM, Chiswell B and Moore MR, 1999, Tumours in mice induced by exposure to sodium arsenate in drinking water. Book Chapter in: Arsenic Exposure and Health Effects. Eds. C Abernathy, R Caldron & W Chappell. Elsevier Science, UK. pp 217-223.
  10. Ng J.C., Kratzmann S.M., Qi L., Crawley H., Chiswell B. and Moore M.R., 1998, Speciation and bioavailability: risk assessment arsenic contaminated sites in a residential suburb in Canberra. Analyst,123: 889-892.

Facilities

A brand new high sensitivity HPLC-ICP-MS funded by ARC-LIEF grant has been installed at EnTox for multi-elemental analysis and metal speciation. This instrument is being utilised by more than 12 PhD projects and a number of post doctoral fellows within EnTox and by its partners from other organisations.

EnTox is co-located within the Queensland Health Scientific Services campus where we can access to the state of art animal house facility.