Research Network for Metals in Medicine



Prof. Ian Brereton

Position: Deputy Director, Senior Research Fellows

Affiliation: University of Queensland, Centre for Magnetic Resonance

Postal Address:
Centre for Magnetic Resonance
Level 2, Gehrmann Laboratories
Research Road
University of Queensland
Brisbane Qld 4072

Phone: +61 (07) 3365 4245
Fax: +61 (07) 3365 3833

Research Profile

  • Pulse sequence design and implementation for applications in high-resolution NMR spectroscopy
  • Molecular structure determination in chemical and biochemical applications
  • Technique development in localised NMR spectroscopy

Selected Publications

  1. Quadrature Detection in F1 Induced by Pulsed Field Gradients. I.M. Brereton, S. Crozier, J. Field and D.M. Doddrell, J. Magn. Reson., 93, 54-62 (1991)
  2. High Field Localized 1H Spectroscopy, D.M. Doddrell, I.M. Brereton and S. Crozier. in "Magnetic Resonance Microscopy: Methods and Applications in Materials Science Agriculture and Biomedicine", VCH Publishers, Weinheim, 1992, pp 547-562
  3. Localised Two Dimensional Shift Correlated Spectroscopy in Humans at 2 Tesla. I.M. Brereton, G.J. Galloway, S.R Rose and D.M. Doddrell. Magn. Reson. Med., 32, 251-257, (1994)
  4. Ionization States of the Catalytic Residues in HIV-1 Protease. R. Smith, I.M. Brereton, R.Y. Chai and S.B.H. Kent, Nature Struct. Biol., 3, 946-950 (1996)
  5. Haliclonacyclamines A and B, Cytotoxic Alkaloids from the Tropical Marine Sponge Haliclona sp. R.D. Charan, M.J. Garson, I.M. Brereton, A.C. Willis and J.N.A. Hooper, Tetrahedron, 52, 9111-9120 (1996)
  6. Sample-Induced RF Perturbations in High Field, High Resolution NMR Sectroscopy. S. Crozier, I.M. Brereton, F.O. Zelaya, W.U. Roffmann and D.M. Doddrell, J. Magn. Reson., 126, 39-47, (1997)
  7. Spectrometer Calibration and Experimental Setup: Basic Principles and Procedures. I.M. Brereton, in Techniques in Protein NMR, Humana Press, Totowa, New Jersey, U.S.A. Methods. Molec. Biol., 60, 363-410 (1997)
  8. The Structure of Galactosyl Ononitol. A. Richter, T. Peterbauer and I.M. Brereton, J. Natural Products, 60, 749-751 (1997)
  9. Structure of Caribbean Ciguatoxin Isolated from Caranx latus. R.J. Lewis, J-P. Vernoux and I.M. Brereton, J. Am. Chem. Soc., 120, 5914-5920 (1998)
  10. Calcium is Essential for the Structural Integrity of the Cysteine-Rich, Ligand-Binding Repeat of the Low-Density Lipoprotein Receptor. A.R. Atkins, I.M. Brereton, P.A. Kroon, H.T. Lee and R. Smith, Biochemistry, 37, 1662-1670 (1998)
  11. NMR Studies of the low density lipoprotein receptor-binding peptide of apoliprotein E bound to dodecylphosphocholine micelles. D. Clayton, I.M. Brereton, P.A. Kroon and R. Smith, Protein Sci. in press, (1999)